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RAGE Rabbit Monoclonal Antibody |
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Description |
Recombinant Rabbit Monoclonal Antibody |
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Conjugation |
Unconjugated |
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Modification |
Unmodified |
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Isotype |
IgG, Kappa |
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Clonality |
Monoclonal |
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Form |
Liquid |
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Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
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Buffer |
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%protective protein |
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Purification |
Protein A |
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Gene Name |
AGER |
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Gene ID |
177 |
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SwissProt ID |
Q15109 |
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Alternative Names |
AGER;RAGE;Advanced glycosylation end product-specific receptor;Receptor for advanced glycosylation end products |
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Dilution Ratio |
WB 1:2000-1:10000,IHC 1:200-1:1000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200 |
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Molecular Weight |
Calculated MW:43kD;Observed MW:52,58kD |
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Background |
Cell localization:[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Isoform 10]: Cell membrane ; Single-pass type I membrane protein ..The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene |
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Validated Image |
A431 cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with RAGE Rabbit Monoclonal Antibody 1:1000. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.
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