| NGS Clean-Up Magnetic Bead Systems | ||
| BSCS | CleanSeq Beads | NGS magnetic particle - removal of free fluorescent dye from sequencing solution ( Replace Beckmen or agencourt CleanSeq) |
| BSP | MagPure A4 XP | NGS magnetic beads - Recover DNA from PCR & enzyme reactions (Replace Beckmen or agencourt Ampure XP) Can be used in NGS library construction |
| BSRP | RNA Clean Beads | Recovery of RNA from RNA reaction solution by magnetic bead method (Replace Beckmen RNAClean XP) |
| BSBXP | MagPure A3 | NGS magnetic beads - Recover DNA from PCR & enzyme reactions, selective removal of dimers or redundant fragments below 300bp (Replace Beckmen or agencourt Ampure) |
| BSXP | MagSelect Beads | NGS magnetic beads - DNA Clean Up from PCR & enzyme reactions (Replace Beckman or agencourt AmPure SPRISelect) |
NGS Clean-Up Magnetic Bead Systems
Introduction
- Magnetic bead-based clean-up systems are widely used in post-reaction nucleic acid workflows, particularly for PCR product purification, fragment size selection and sequencing reaction clean-up. These processes help remove residual primers, enzymes, salts and other reaction components prior to downstream analysis.
- Within the Magen portfolio, clean-up bead systems are developed based on PEG-mediated binding chemistry, enabling selective adsorption of nucleic acids under controlled conditions. Depending on bead configuration and workflow parameters, these systems support routine DNA/RNA purification as well as more specialized applications such as fragment size control in NGS library preparation.
- Different bead configurations are optimized for distinct workflow stages, including routine clean-up, selective removal of short fragments, RNA purification and sequencing reaction purification. This allows laboratories to build flexible and reproducible workflows across molecular biology and sequencing applications while maintaining compatibility with both manual handling and automated platforms.