anti- Caspase 8 antibody
$350.00
| Catalogue No. | 39210FNab |
| Size | 100µg / liquid Form |
| Synonyms | Apoptotic cysteine protease, Apoptotic protease Mch 5, Casp 8, CASP8, Caspase 8, Caspase 8/p18, Caspase8, FADD like ICE, FLICE, ICE like apoptotic protease 5, MACH, MCH5 |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Isotype: | IgG |
| Tested Application: | ELISA, WB, IHC, IP, IF |
Description
| Product Name | anti- Caspase 8 antibody |
| Catalogue No. | 39210FNab |
| Size | 100µg |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
BACKGROUND
| Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3(PMID:21816816). It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. This antibodycan recognize pro-and cleaved-caspase 8. |
IMMUNOGEN INFORMATION
| Immunogen | caspase 8, apoptosis-related cysteine peptidase |
| Observed MW | 50-55 kDa, 25-32 kDa |
APPLICATION
| Tested Application | ELISA, WB, IHC, IP, IF |
| Recommended Dilution | WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:50-1:100; IF: 1:10-1:100 |
IMAGES
| Immunohistochemistry of paraffin-embedded human lymphoma using 39210FNab (CASP8 antibody) at dilution of 1:50 |  |
| Immunofluorescent analysis of ( -20℃ Ethanol ) fixed HepG2 cells using 39210FNab (Caspase 8 Antibody）at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG |  |
| IP Result of anti-CASP8 (IP:39210FNab, 3ug; Detection:39210FNab 1:500) with HeLa cells lysate 2500ug. |  |
| HepG2 cells were subjected to SDS PAGE followed by western blot with 39210FNab (CASP8 antibody) at dilution of 1:1000 |  |
Additional information
| Pack Size | 100µg / liquid Form |
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