anti- Caspase 1 antibody
$360.00
Product Name: anti- Caspase 1 antibody
Catalog No.: BS-48210BANF
Synonyms: CASP 1, CASP1, Caspase 1, Caspase 1/p20/p10, Caspase1, ICE, IL 1 beta converting enzyme, IL 1BC, IL1BC, IL1BCE, Interleukin 1 beta convertase, p10, p20, P45
Host: Rabbit
Reactivity: Human, Mouse, Rat
Isotype: IgG
Tested Application: ELISA, WB, IHC
DatasheetDescription
PRODUCT INFORMATION
Product Name: anti- Caspase 1 antibody
Size: 100µg
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND: CASP1 (caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta (IL1B) , IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products (PMID:21804020) . It has 5 isoforms produced by alternative splicing.
IMMUNOGEN INFORMATION
Immunogen: caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
Synonyms: CASP 1, CASP1, Caspase 1, Caspase 1/p20/p10, Caspase1, ICE, IL 1 beta converting enzyme, IL 1BC, IL1BC, IL1BCE, Interleukin 1 beta convertase, p10, p20, P45
Observed MW: 45-47 kDa, 30 kDa, 35 kDa
APPLICATION
Tested Application: ELISA, WB, IHC
Recommended Dilution: WB: 1:500-1:2000, IHC: 1:20-1:200
human spleen tissue slide using BS-
48210BANF(Caspase 1 Antibody) at dilution of
1:100
by western blot with BS-48210BANF(CASP1
antibody) at dilution of 1:1000
Additional information
| SIZE | 100µg-liquid |
|---|
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